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Application Note: A New Technology for Highly Efficient and Reproducible Albumin Depletion from Whole Serum

One of the major problems faced in the analysis of the human serum proteome is the broad dynamic range of its protein constituents. High abundance proteins, such as human serum albumin (HSA) and gamma-immunoglobulin (IgG), which together comprise 75% of total serum protein content, inhibit the analysis of lower abundance proteins of interest. Current research is centered on performing proteomics analysis of serum/plasma for the characterization of proteins in human serum, as well as the discovery of new biomarkers.

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